Aesthetic Dermatology

Histological evidence of new collagen formulation with platelet-rich plasma in skin rejuvenation.³

In this prospective, controlled clinical trial, the authors evaluated the efficacy of intradermal injection of Regen PRP for facial rejuvenation in humans (20 patients) by performing pre- and post-treatment histological examinations and measuring collagen mean optical densities (MODs).

Revitalisation of the face and neck with platelet-rich plasma⁵

In this case series of 23 patients, the authors investigated whether there were real results, benefits and side effects following a standardised PRP injection protocol. DGS was calculated by comparing the spider improvement score, pre- and post-improvement photos, patient satisfaction score and physician satisfaction score. Patients received a RegenPRP injection once a month for three months. Patients were assessed one month after the last injection. A final graduated score (DGS) was calculated for each patient.

Application of regenerative medicine in the treatment of acne scars.⁶

The efficacy of nanofat and plasma rich platlets injection and fractional CO2 laser resurfacing was studied in 30 patients.⁶

Injection of platelet-rich plasma is an effective and safe method as adjunctive therapy to resection in the treatment of keloid scars that are insensitive to conventional therapy.⁷

The efficacy of Regen PRP for the treatment of keloid scars was evaluated in 17 patients. Assessment was based on complete remission of keloid scars, pruritus severity score and mean Vancouver Scar Scale (VSS) score, two years after treatment with Regen PRP.

Significant improvement in skin elasticity. ^1-2

In a prospective study, 31 patients were treated at 0, 1 and 2 months with mesotherapy using the combination of Regen PRP and HA produced by CELLULAR MATRIX (CM-PRP-HA). Clinical benefit was assessed using FACE-Q scores and biophysical measurements of skin elasticity.

Comparison of FACE-Q scores showed significant improvement at 6 months compared to baseline (p=0.03). Similarly, objective biophysical measurements showed a significant improvement in skin elasticity (R5) compared to baseline (p=0.036) 6 months after treatment.

No serious side effects were observed.

Cellular Matrix  improves skin tone and quality.²

A prospective study of 5 patients investigated the clinical benefits of the combination of Regen PRP and HA produced by CELLULAR MATRIX (CM-PRP-HA) when used as mesotherapy on the hand and face. Assessments of skin quality and tone were conducted by both treated subjects and reviewers.

Significant improvement of the skin on the hands and face was observed in all subjects, including improvement in skin quality and tone and wrinkle depth after three treatment sessions.

No serious side effects were noted. Discomfort at the injection site and bruising (lower eyelid and back of the hand) were reported.

The combination of Regen PRP and HA provides better contouring and appears to accelerate cellular regeneration, making this combination the right tool for skin hydration.^10-11

CM-PRP-HA can be used either as a stand-alone treatment, injected directly into the superficial dermis, or together with deeper injection into the superficial musculoaponeurotic system (SMAS).^10-11

HA acts as a bioscaffold, increasing the residence time of growth factors in the tissue and promoting cell migration and regeneration. CM-PRP-HA facilitates volume balancing and lifting and provides an immediate result.^9-10-11